Vaccination for Prevention of Human Papillomavirus (HPV) Infection and Its Sequelae

Faculty

Needs Statement

STDs are common, costly, and preventable. Worldwide, an estimated 333 million cases of curable STDs occur annually. In 1995, STDs were the most common reportable diseases in the United States. They accounted for 87 percent of the top 10 infections most frequently reported to the Centers for Disease Control and Prevention (CDC) from State health departments. Of the top 10 infections, 5 were STDs (chlamydia, gonorrhea, AIDS, syphilis, and hepatitis B). Each year an estimated 15 million new STD infections occur in the United States, and nearly 4 million teenagers are infected with an STD. The direct and indirect costs of the major STDs and their complications, including sexually transmitted HIV infection, are conservatively estimated at $17 billion annually.

Despite recent progress toward controlling some STDs, when compared to other industrialized nations, the United States has failed to go far enough or fast enough in its national attempt to contain acute STDs and STD-related complications. STD rates in this Nation exceed those in all other countries of the industrialized world (including the countries of western and northern Europe, Canada, Japan, and Australia). Through a sustained, collaborative, multifaceted approach, other countries have reduced significantly the burden of STDs on their citizens, an accomplishment the United States also should strive to achieve.

The estimated annual incidence of sexually transmitted HPV infection is 6.2 million cases.  It is estimated that at least 50% of sexually active men and women acquire genital HPV infection at some point in their lives. An estimated 20 million people currently have a detectable genital HPV infection.

Target Audience

Physicians, physician assistants, nurse practitioners, nurse mid-wives, nurses, pharmacists.

Objectives

1.  Describe the epidemiology of HPV in the U.S.;
2.  Describe the pathology of HPV;
3.  Discuss the clinical manifestations of genital HPV infection;
4.  Identify methods used to diagnosis genital warts and cervical cellular abnormalities;
5.  List the CDC-recommended treatment regimens for HPV;
6.  Describe public health measures for the prevention of HPV including vaccines.

Accreditation

CME
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the University of Kentucky College of Medicine and The Alabama/North Carolina STD Prevention and Training Center. The University of Kentucky College of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

The University of Kentucky College of Medicine designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

The University of Kentucky College of Medicine presents this activity for educational purposes only. Participants are expected to utilize their own expertise and judgment while engaged in the practice of medicine. The content of the presentations is provided solely by presenters who have been selected for presentations because of recognized expertise in their field.

CNE
This activity is co-provided by the University of Alabama at Birmingham, Department of Medicine, Alabama AIDS Training & Education Center, which is approved by the Alabama State Nurses Association, which is accredited as an approver of continuing education in nursing by the American Nurses Credentialing on Accreditation and the Alabama Board of Nursing. This course is approved for 1.00 Continuing Education hour.

Faculty Disclosure

Dr. Hook is an investigator and speaker for GlaxoSmithKline, an investigator and consultant for Abbott, an investigator for Gen-Probe and Becton Dickinson, a consultant for MedHelp and a speaker for Merck.

Activity Sponsorship

This activity is jointly sponsored by the University of Kentucky and The Alabama/North Carolina STD Prevention and Training Center.